THE SCIENCE BEHIND HOW IT WORKS
The Science behind: How the Hair Grows:
The Hair Growth Cycle consists of 3 phases: Anagen, Catagen and Telogen.
Anagen is the Growing Phase and in this phase the hair is full of life, it’s growth is constant, and the root fills the hair follicle all the way to the base.
Hair cells are produced in the Dermal Matrix; the production of ATP energy causes an active cell to divide, therefore producing the hair cells. The hair cells gradually work their way up in to the Inner Root Sheath and out of the hair follicle to become new hairs.
The average length of time that each follicle will stay in the Anagen Phase is 3 to 6 years, depending on an individual’s genetics.
Catagen is known as the Resting Phase as the hair stops growing. Approximately 3% of the hairs on your scalp are in this phase at any time. Catagen lasts for 1 – 2 weeks.
Telogen is the Shedding Phase. At this point the hair detaches from the hair follicle and the follicle shrinks. However, the hair may not shed until the root of the hair replacing it is strong enough to remove it.
The Telogen Phase usually lasts 5 – 6 weeks and it can be normal to shed 40 – 150 hairs per day. This is not considered Hair Loss.
The Science behind: How Capixyl works:
One of the active ingredients in the 360 OPTIMUM HAIR Shampoo, Conditioner and Treatment Serum is Capixyl. Capixyl is a unique and innovative complex produced using a combination of a biomimetic signal peptide, Acetyl Tetrapeptide-3, with a red clover extract, rich in Biochanin A. It has been proven to promote the Anagen ‘Growing’ Phase and reduce the Telogen ‘Shedding’ Phase of the Hair Growth Cycle.
The combination of the 2 ingredients work in the following ways; Firstly, to improve extracellular matrix (ECM) proteins in the dermal papilla, which provides better hair anchoring and reduces damage that is caused by inflammation. This will provide stronger, fuller and healthier looking hair.
Secondly, Capixyl is able to bind to the 5-alpha-reductase enzyme. This means that when the DHT hormone attaches to the androgen receptors at the hair follicle it provides the follicle with the ingredients needed to feed the follicle.
The Science behind: How Low Level Laser Therapy works:
Low Level Laser Therapy (LLLT) is also known as Photobiomodulation or Photobiostimulation and is used to stimulate and enhance cell function. The specific wave length approved for stimulating Hair Growth is 630nm-670nm because it has the ability to be absorbed by the molecules of the hair follicle, and can therefore penetrate the scalp to stimulate the epidermal stem cells to regenerate the hair follicles.
The increase in blood flow to the area promotes the delivery of oxygen and nutrients to the hair follicles. LLLT has an effect on the metabolic process, specifically the mitochondria. It stimulates the production of Adenosine Triphosphate (ATP) by opening the cytochrome c oxidase pathway. The function of ATP is to transport chemical energy within cells for metabolism.
An increase in ATP energy activates cellular factors including cytokines and growth factors resulting in the follicle staying in the Anagen ‘Growing’ Phase for longer. Refer to ‘The Science behind: How the Hair Grows’ to understand this further.
Low Level Laser Therapy is the only non-medication treatment approved by the FDA and has no adverse side effects. Due to the type of Laser diodes used there is no burning, cutting or pain. These types of devices are referred to as ‘cool’ lasers for this reason.
The Science behind: How DHT causes Hair Loss:
DHT is an active metabolite of the hormone Testosterone. It travels through our blood stream and attaches itself to the base of the hair follicle on the androgen receptors. Androgen receptors pass food and oxygen to the hair follicle.
When DHT is attached, the follicle cannot get the nutrition and oxygen it needs to grow or survive.
In time the follicle begins to shrink in size. The hair growing from the follicle becomes thinner, until eventually the thin weakened hair will shed. Eventually the follicle fails to produce a new hair and the follicle becomes inactive.
The Science behind: How Minoxidil works:
Minoxidil is a vasodilator medication and its effect on Hair Loss was discovered during clinical trials for high blood pressure treatment. When taken orally in pill form it dilates arteries in the body causing blood flow to decrease. It was noted to, particularly in Women, cause hypertrichosis (excessive hair growth) and the manufacturers went on to develop a topical formulation to be applied to the scalp without causing arteries throughout the body to dilate as with the oral medication. The topical form of Minoxidil was then given FDA approval to treat Hair Loss.
Minoxidil increases blood flow, oxygen and nutrients to the follicle, and is thought to widen the hair follicle, and promote the Anagen ‘Growing’ Phase.
Refer to ‘The Science behind: How the Hair Grows’ to understand this further.
Regaine is the only over the counter brand of Minoxidil that is licensed to be retailed in the UK. It contains a 2% or 5% strength of Minoxidil. 360 Hair Clinic can offer private prescriptions of 6% or 12.5% strength Minoxidil for those that are deemed medically suitable.